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Steven D Shnyder Selected Research

ICT2588

4/2014Tumor-targeted prodrug ICT2588 demonstrates therapeutic activity against solid tumors and reduced potential for cardiovascular toxicity.
9/2010Development of a novel tumor-targeted vascular disrupting agent activated by membrane-type matrix metalloproteinases.

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Steven D Shnyder Research Topics

Disease

26Neoplasms (Cancer)
01/2022 - 11/2004
6Colonic Neoplasms (Colon Cancer)
06/2013 - 11/2004
4Neoplasm Metastasis (Metastasis)
07/2020 - 12/2011
3Ovarian Neoplasms (Ovarian Cancer)
01/2022 - 11/2010
3Head and Neck Neoplasms (Head and Neck Cancer)
01/2021 - 05/2017
3Necrosis
01/2017 - 08/2007
3Carcinoma (Carcinomatosis)
12/2012 - 11/2005
2Malaria
01/2022 - 01/2021
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2022 - 01/2019
2Lung Neoplasms (Lung Cancer)
01/2019 - 01/2016
2Hypoxia (Hypoxemia)
01/2018 - 12/2009
2Small Cell Lung Carcinoma (Small Cell Lung Cancer)
07/2013 - 01/2013
2Adenocarcinoma
10/2012 - 12/2006
1African Trypanosomiasis (Nagana)
01/2022
1Trypanosomiasis
01/2021
1Infections
01/2021
1Inflammation (Inflammations)
10/2020
1Bacterial Infections (Bacterial Infection)
10/2020
1Squamous Cell Carcinoma of Head and Neck
05/2017
1Glioma (Gliomas)
01/2016
1Neuroblastoma
01/2013
1Pancreatic Neoplasms (Pancreatic Cancer)
01/2013
1Prostatic Neoplasms (Prostate Cancer)
10/2012
1Breast Neoplasms (Breast Cancer)
11/2011
1Disease Progression
11/2011
1Carcinogenesis
08/2008

Drug/Important Bio-Agent (IBA)

6Pharmaceutical PreparationsIBA
05/2021 - 12/2012
5EnzymesIBA
01/2021 - 10/2007
5ProdrugsIBA
04/2014 - 11/2004
4polysialic acidIBA
05/2021 - 01/2013
3cryptolepineIBA
01/2022 - 10/2007
3Doxorubicin (Adriamycin)FDA LinkGeneric
01/2022 - 09/2010
3Cisplatin (Platino)FDA LinkGeneric
01/2022 - 03/2010
3Cytotoxins (Cytolysins)IBA
01/2016 - 12/2009
3DNA (Deoxyribonucleic Acid)IBA
11/2011 - 11/2006
22,7-dibromocryptolepineIBA
01/2022 - 04/2005
2Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
01/2021 - 06/2013
2IntegrinsIBA
05/2017 - 10/2012
2ICT 2552IBA
01/2016 - 09/2010
2ICT2588IBA
04/2014 - 09/2010
2DuocarmycinsIBA
08/2013 - 06/2013
2Neural Cell Adhesion Molecules (Neural Cell Adhesion Molecule)IBA
07/2013 - 01/2013
2TubulinIBA
12/2012 - 12/2012
2auristatin PYEIBA
03/2010 - 08/2007
1RutheniumIBA
01/2022
1AlkaloidsIBA
01/2022
1Antimalarials (Antimalarial Agents)IBA
01/2022
1LigandsIBA
01/2022
1maleinitriledithiolateIBA
01/2022
1phosphine (phosphane)IBA
01/2022
1Coordination ComplexesIBA
01/2022
1endo-alpha-sialidaseIBA
05/2021
1N-Acetylneuraminic Acid (Sialic Acid)IBA
05/2021
1Polysaccharides (Glycans)IBA
05/2021
1Protein Isoforms (Isoforms)IBA
01/2021
1CarcinogensIBA
01/2021
1Formyl Peptide Receptors (Formyl Peptide Receptor)IBA
10/2020
1Chir 99021IBA
01/2019
1Paclitaxel (Taxol)FDA LinkGeneric
01/2019
1Glycogen Synthase (Synthase I)IBA
01/2019
1Proteins (Proteins, Gene)FDA Link
01/2018
1Glycine (Aminoacetic Acid)FDA LinkGeneric
05/2017
1Aspartic Acid (Aspartate)FDA Link
05/2017
1Arginine (L-Arginine)FDA Link
05/2017
1Oxepins (Oxepin)IBA
01/2017
1dibenzyl etherIBA
01/2017
1von Willebrand FactorIBA
04/2014
1Indicators and Reagents (Reagents)IBA
04/2014
1Peptides (Polypeptides)IBA
04/2014
1Cytochrome P-450 CYP1A1 (CYP1A1)IBA
08/2013
1cyclopropapyrroloindoleIBA
08/2013
1Histones (Histone)IBA
06/2013
1(1- (chloromethyl)- 1,2- dihydropyrrolo(3,2- e)indol- 3(6H)- yl)(5- fluoro- 1H- indol- 2- yl)methanoneIBA
06/2013
1(5- chloro- 1H- indol- 2- yl)(1- (chloromethyl)- 1,2- dihydropyrrolo(3,2- e)indol- 3(6H)- yl)methanoneIBA
06/2013
1Mixed Function Oxygenases (Monooxygenases)IBA
06/2013
1(3,4-difluorobenzyl-N-aminocolchicine)IBA
12/2012
1ColchicineFDA LinkGeneric
12/2012
1Dihydrotachysterol (AT 10)IBA
12/2011
1CYT997IBA
12/2011
1bisbenzimide ethoxide trihydrochloride (Hoechst 33342)IBA
12/2011
1Fluorescent Dyes (Fluorescent Probes)IBA
12/2011
1Antineoplastic Agents (Antineoplastics)IBA
11/2011
14-cymene (p-cymene)IBA
11/2010
1diphenyl (biphenyl)IBA
11/2010
1OsmiumIBA
11/2010
1Matrix Metalloproteinase 14 (MT1-MMP)IBA
09/2010
1Membrane-Associated Matrix MetalloproteinasesIBA
09/2010
1Oxygen (Dioxygen)IBA
09/2010
1AQ4NIBA
12/2009
1ProteomeIBA
08/2008
1Biomarkers (Surrogate Marker)IBA
08/2008
1pancratistatinIBA
03/2008
1Phosphates (Orthophosphate)IBA
03/2008
1SodiumIBA
03/2008
1NRH - quinone oxidoreductase2IBA
10/2007
1C 1311IBA
12/2006

Therapy/Procedure

6Therapeutics
01/2019 - 11/2004
2Drug Therapy (Chemotherapy)
01/2019 - 06/2013
1Chemoradiotherapy
12/2009
1Aftercare (After-Treatment)
08/2007